Open Pipelines

single-cell
spatial
multiomics
pipelines
reproducibility
workflow
Nextflow
Modular, reproducible pipelines for single-cell and spatial data
Authors

Dries Schaumont

Dorien Roosen

Jakub Majercik

Luke Zappia

Robrecht Cannoodt

Toni Verbeiren

Data Intuitive

Open Pipelines contributors

Date

January 26, 2026

Links
Open Pipelines logo

Open Pipelines is an open-source effort to develop modular, reproducible pipelines for single-cell multiomics and spatial data analysis. The workflows aim to reliably and robustly process raw data to an interpretable, analysis-ready format, while being flexible enough to adapt to user needs.

The project is built on Viash and hosted on Viash Hub, allowing it to be truly modular and generate scalable and portable Nextflow workflows.

I contribute to the project as part of my work at Data Intuitive, adding new functionality, improving components and workflows and giving input on the design and development of the project. These repositories are also used as the foundation for private pipelines developed for pharmaceutical companies, as well as internal projects.